Experimental study on the osseointegration of nanophase hydroxyapatite biograde-coated implants / 中华外科杂志

<p><b>OBJECTIVE</b>To study the osseointegration of the nanophase hydroxyapatite biograde-coated implants and host bone.</p><p><b>METHODS</b>Nanophase hydroxyapatite biograde-coated implants, hydroxyapatite biograde-coated implants and noncoated Ti-6Al-4V implants were inserted into both femoral of Beagle canines the tissue response, dynamic osteogensis and SEM were studied at 4, 8 and 12 weeks.</p><p><b>RESULTS</b>The degradation of nanophase hydroxyapatite was slower than hydroxyapatite, dynamic osteogensis and the form of osteoblast were better than the control groups.</p><p><b>CONCLUSION</b>The biological reaction of Nanophase hydroxyapatite biograde-coated implants is better than hydroxyapatite coated implant.</p>